Our new Crystal clear+ tissue clearing strategy is the sole technique that delipidates samples with no transform in morphology and with small influence on structural integrity.
Megatome is usually a vibrating microtome meant to part a wide selection of samples, from organoids and biopsy samples to expanded rodent brains and intact human organs. With higher blade vibrating frequency and minimized blade deflection, Megatome permits large-throughput tissue sectioning with uniform surface area profile, in addition to negligible tissue damage and data loss.
Request a quote or demo Uniformly segment large tissues & sample arrays Megatome is the one microtome that could section samples as huge as intact nonhuman primate and human organs, rendering it priceless for fields like neuropathology.
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SE utilizes a rotational electrical field to disperse remarkably electromobile molecules (like antibodies or surfactant micelles) all over a porous sample with no harmful electrically billed buildings inside the tissue. This allows two-four day clearing of intact organs,
Our preformulated EasyIndex solution raises and homogenize the refractive index of delipidated tissue samples, rendering them entirely clear. This enables mild penetration in the sample and ensures the acquisition of large-resolution, in-emphasis graphic data.
Megatome can be a novel microtome that enables for top-precision sectioning of a variety of tissue samples – from organoids, to arrays of animal organs, to intact human Mind hemispheres – with minimal tissue damage and information loss.
It’s time for you to update your microtome to Megatome. With correct substantial-frequency slicing for an unmatched number of sample sizes and types – from organoids and tumors to expanded tissues, sample arrays, and intact primate organs – Megatome is optimized for numerous purposes.
The SmartSPIM light-weight sheet microscope presents unparalleled resolution and acquisition velocity all over intact tissue volumes, when its modular style and design means that you can up grade and personalize specific parts.
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SHIELD avoids the variability of hydrogel embedding and the knowledge loss from PFA preservation, preserving specimens for a number of rounds of processing.
Leverage the Clear+ tissue clearing strategy, together with eFLASH and patented stochastic electrotransport systems, to rapidly obvious megatomi.com and label whole organs. Essential highlights and attributes include things like:
Our novel SHIELD tissue preservation procedure types intramolecular bonds working with polyfunctional, flexible epoxides to stabilize tissue architecture and safeguard the sample’s endogenous fluorescence, protein antigenicity and nucleic acids.